Unverified50% confidenceOpinionExact time
During reprogramming, cells undergo drastic epigenetic remodeling, DNA methylation patterns are globally remodeled, and many aging-related methylation sites are reset, which may be the direct cause of the significant decrease in epigenetic clock readings.
1
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50%
Confidence
Long-term
Relevance
10/13/2026
First Seen
Sources
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