Unverified50% confidenceFactExact time

Between 2 a.m. and 5 a.m., core body temperature is at its low point, melatonin levels rise, and metabolic activity in the prefrontal cortex drops significantly.

1

Sources

50%

Confidence

Long-term

Relevance

10/31/2026

First Seen

Sources

Don't Trust Any of Your Thoughts Between 2 AM and 5 AM

youtubeAndrew Huberman10/31/2026

Related Entities

Prefrontal Cortexconcept

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