Unverified85% confidenceDecision RuleTime unknown

生理性剂量0.3-0.5mg对入睡困难的效果不逊于3-5mg，且次日残留嗜睡感更低，成年人首次尝试应从0.5mg起而非常见的3-5mg

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85%

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Long-term

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褪黑素category

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Unverified首次使用或对时差/入睡困难，优先选0.5-1mg低剂量，研究显示0.3-0.5mg即可有效缩短入睡时间，高于此剂量并不提升助眠效果反而增加次日头晕、宿醉感风险93% similar Unverified剂量越高越易造成受体脱敏和白天嗜睡，但极低剂量（0.3mg）对严重节律紊乱者可能不足；节律调整需求可到2-3mg，纯入睡问题0.5mg起试92% similar

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