Unverified90% confidenceFactTime unknown
TREM2的功能缺失突变（如R47H）被GWAS确认为阿尔茨海默症最强的单基因风险因子之一，携带者患病风险提高2-4倍
1
Sources
90%
Confidence
Long-term
Relevance
6/1/2026
First Seen
Sources
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