Unverified85% confidenceCautionTime unknown
肾功能不全或有肾结石(草酸钙结石)病史者不建议长期服用1000mg以上大剂量维C，维C代谢产物草酸盐会增加结石风险
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Unverified肾功能不全或有肾结石病史者应避免长期大剂量（≥1000mg/日）维C，因维C代谢产物草酸会增加草酸钙结石风险，此类人群应控制在≤200mg/日90% similarUnverified有肾结石（尤其草酸钙结石）病史者不建议长期大剂量补维C，维C代谢会增加尿草酸，每日应控制在500mg以内并优先食物来源89% similarUnverified肾功能不全或透析患者不建议大剂量补维C（>200mg/天），过量维C代谢产生的草酸会加重肾脏负担并可能引发草酸盐沉积88% similarUnverified肾功能不全或有肾结石（尤其草酸钙结石）病史者不建议长期高剂量（≥1000mg/天）补充维生素C，因过量VC代谢产生草酸盐，增加肾结石风险85% similarUnverified肾功能不全人群不建议选含高剂量VC(>1000mg)+高钾/高磷辅料的复合配方，VC代谢产物草酸盐会加重肾脏负担，应选低剂量、无钠无钾配方84% similar
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