Unverified85% confidenceCautionTime unknown
红曲不可与葡萄柚汁、大量西柚同服，也应避免与贝特类降脂药、环孢素、某些抗生素(红霉素等)联用，这些会通过CYP3A4酶抑制升高血药浓度，增加肌毒性
1
Sources
85%
Confidence
Long-term
Relevance
-
First Seen
Sources
Related Entities
Related Claims
Unverified红曲提取物与葡萄柚汁同服会抑制CYP3A4酶，升高莫纳可林K血药浓度增加毒性；服用期间应避免大量葡萄柚制品89% similarUnverified服用他汀类、部分降压药（如硝苯地平、非洛地平）时避免选用葡萄柚/西柚味的服药凝胶或果泥，柚苷会抑制CYP3A4导致药物血药浓度升高87% similarUnverified辛伐他汀、洛伐他汀、阿托伐他汀经CYP3A4代谢，与克拉霉素、伊曲康唑、部分抗艾滋药及大量西柚汁同服会升高血药浓度增加毒性；瑞舒伐他汀和普伐他汀不经CYP3A4，相互作用更少，多药联用者优选80% similarUnverified服用华法林等抗凝药者禁与丹参、当归、银杏叶类中成药联用，会增强抗凝导致出血风险；服降糖药者慎用含甘草的中成药（可能升糖并致水钠潴留）70% similarUnverified正在服用抗凝血药物（如华法林）者应避免含当归、丹参、川芎等活血药材的汤料包，可能增强药效导致出血风险66% similar
Cite This Claim
Stable URI
https://kongchang.com/claim/266344API
curl https://kongchang.com/api/v1/knowledge/claims/266344MCP
get_claim(id=266344)