Verified65% confidenceFactExact time
Biological age is estimated based on epigenetic markers such as DNA methylation patterns, referred to as the epigenetic clock.
3
Sources
65%
Confidence
Long-term
Relevance
9/11/2026
First Seen
Sources
Related Entities
Related Claims
Unverified大脑老化生物标志物涵盖端粒长度、DNA甲基化时钟（如Horvath时钟）、衰老细胞比例、白质完整性、脑脊液Aβ42/tau比值、认知测试评分、海马体积等多个层次77% similarUnverifiedThe Horvath Clock predicts chronological age by detecting the methylation status of hundreds of CpG sites.73% similarUnverifiedSteve Horvath proposed the Horvath Clock in 2013, which is foundational work in the field of biological age measurement.72% similarUnverifiedBiological age attempts to reflect the true degree of aging at the cellular, tissue, and organ levels of the body.71% similarUnverifiedResearchers have successively developed next-generation clocks such as GrimAge and PhenoAge, which not only predict age but also more effectively correlate with disease risk and mortality.71% similar
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