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Concept细胞绘画

Cell Painting

A high-content imaging assay developed by the Broad Institute that uses six fluorescent dyes to label multiple organelles and structures, producing multichannel images and thousands of morphological features for gene function annotation, toxicity prediction and phenotypic screening.

Timeline (last 90 days)

Oct 22

The JUMP-CP dataset is generated by the Cell Painting assay, which simultaneously stains different organelles of cells with multiple fluorescent dyes to capture morphological information.

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Oct 22

Cell Painting is a high-content imaging assay developed and promoted by the Broad Institute, using six fluorescent dyes to stain the nucleus, endoplasmic reticulum, nucleolus, Golgi apparatus and plasma membrane, mitochondria, and actin cytoskeleton, respectively.

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Oct 22

A single Cell Painting imaging run can produce images in five fluorescent channels, covering thousands of morphological features such as cell morphology, texture, and intensity distribution.

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