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Conceptnatural experiment

Natural Experiment

A research design in epidemiology that uses approximately random grouping produced by external rules or events to compare outcomes across populations; it approximates a randomized controlled trial but retains limitations.

Timeline (last 90 days)

Oct 21

A natural experiment based on an age cutoff found that people eligible for the shingles vaccine appeared to have a lower chance of developing Alzheimer's disease.

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Oct 21

Natural experiments use external rules (such as age thresholds) to create approximately random groupings, which can reduce confounding bias but cannot rule out limitations such as the healthy vaccinee effect.

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Oct 15

This measurement is a natural experiment rather than a controlled experiment and should be treated as a lower bound on variance.

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