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ConceptVZV / Varicella-zoster virus

Varicella-Zoster Virus

The virus that causes chickenpox and shingles; after initial infection it lies dormant in nerve ganglia, and reactivation can lead to shingles.

Timeline (last 90 days)

Oct 21

Shingles is caused by reactivation of the varicella-zoster virus (VZV), which lies dormant in ganglia after initial infection.

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Oct 21

One hypothesis holds that VZV reactivation may indirectly affect the central nervous system through neuroinflammation or immune activation, and that the vaccine may provide protection by reducing the frequency of viral reactivation or modulating innate immunity.

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