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ConceptYamanaka factors / OSKM

Yamanaka Factors

The four transcription factors (Oct4, Sox2, Klf4, and c-Myc) identified by Shinya Yamanaka that are used to reprogram somatic cells into induced pluripotent stem cells.

Timeline (last 90 days)

Oct 13

iPSC technology was first reported by Shinya Yamanaka in 2006, and the related transcription factors are called Yamanaka factors.

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Sep 25

Through reprogramming factors (such as partial expression of Yamanaka factors), it is possible to explore achieving a partial reset of the cellular epigenetic clock.

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