Unverified50% confidenceFactExact time
The thalidomide (Contergan) incident is a typical case of a chiral drug tragedy, as the left- and right-handed versions of many drugs have completely different biological activities.
1
Sources
50%
Confidence
Long-term
Relevance
10/12/2026
First Seen
Sources
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Related Claims
UnverifiedThe two enantiomers of the same drug may bind to different receptors in the human body, leading to differences in efficacy or even toxic side effects, which is also an important reason for the thalidomide incident in the 1960s.79% similarUnverifiedOne enantiomer of thalidomide has a sedative effect, while the other carries a risk of teratogenicity.71% similarUnverifiedThe thalidomide incident directly prompted drug regulatory agencies worldwide to require that new drug applications must clearly specify the biological activity and toxicity of each enantiomer.70% similar
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