Unverified85% confidenceCautionTime unknown
肾功能不全或透析患者维C每日摄入应严格控制在60mg以内，过量维C代谢产物草酸会加重肾脏负担，必须遵医嘱
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Unverified肾功能不全或有肾结石病史者应避免长期大剂量（≥1000mg/日）维C，因维C代谢产物草酸会增加草酸钙结石风险，此类人群应控制在≤200mg/日88% similarUnverified肾功能不全或透析患者不建议大剂量补维C（>200mg/天），过量维C代谢产生的草酸会加重肾脏负担并可能引发草酸盐沉积88% similarUnverified有肾结石（尤其草酸钙结石）病史者不建议长期大剂量补维C，维C代谢会增加尿草酸，每日应控制在500mg以内并优先食物来源86% similarUnverified肾结石（草酸钙型）病史或肾功能不全者应避免长期每日超过1000mg，因维生素C代谢终产物草酸会增加结石风险；此类人群建议每日不超过200-500mg79% similarUnverified肾功能不全或有肾结石(草酸钙结石)病史者不建议长期服用1000mg以上大剂量维C，维C代谢产物草酸盐会增加结石风险79% similar
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