Concept2,2'-双(二苯基膦基)-1,1'-联萘
BINAP
A chiral bisphosphine ligand that forms catalysts with metals such as rhodium, used in asymmetric catalytic hydrogenation reactions. It can efficiently generate a single enantiomer and is widely applied in the synthesis of chiral drugs.
Timeline (last 90 days)
Oct 12
The BINAP ligand-rhodium catalyst system developed by William Knowles can efficiently catalyze the hydrogenation of prochiral olefins, generating a single chiral product with extremely high enantioselectivity, and was applied to the industrial production of the Parkinson's disease drug L-DOPA.
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