Conceptcheckpoint inhibitor
Checkpoint Inhibitor
A class of immunotherapeutic drugs that relieves suppression of the immune system by blocking immune checkpoints such as PD-1/PD-L1 and CTLA-4, thereby enhancing attacks on cancer cells; it may induce autoimmune side effects.
Timeline (last 90 days)
Oct 17
Checkpoint inhibitors retrain the immune classifier by releasing the immune system's brakes, and their autoimmune side effects (colitis, pneumonitis, thyroiditis) are false positives of the immune classifier.
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