Product左旋多巴 / Levodopa
L-DOPA
A chiral drug used in the treatment of Parkinson's disease, produced industrially through asymmetric catalytic hydrogenation. It is an important example of the application of chiral synthesis technology.
Timeline (last 90 days)
Oct 12
The BINAP ligand-rhodium catalyst system developed by William Knowles can efficiently catalyze the hydrogenation of prochiral olefins, generating a single chiral product with extremely high enantioselectivity, and was applied to the industrial production of the Parkinson's disease drug L-DOPA.
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