PGC-1α
Known as the master regulator of mitochondrial biogenesis, it plays a central role in the AMPK-PGC-1α pathway activated by endurance exercise.
Timeline (last 90 days)
Endurance exercise promotes mitochondrial proliferation and functional improvement by activating the AMPK-PGC-1α pathway, enhancing muscle oxidative capacity and improving metabolic health.
PGC-1α is called the master regulator of mitochondrial biogenesis; AMPK senses cellular energy status (it is activated when the AMP/ATP ratio rises).
All Facts (2)
Endurance exercise promotes mitochondrial proliferation and functional improvement by activating the AMPK-PGC-1α pathway, enhancing muscle oxidative capacity and improving metabolic health.
50%UnverifiedPGC-1α is called the master regulator of mitochondrial biogenesis; AMPK senses cellular energy status (it is activated when the AMP/ATP ratio rises).
50%