RNA Inverse Design
A class of problems in computational biology aimed at designing RNA sequences that fold into a specified secondary structure, typically evaluated by optimizing the minimum free energy.
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The goal of RNA inverse design is, given a target secondary structure, to find a nucleotide sequence whose minimum free energy (MFE) structure equals the target structure.
RNA inverse design is a combinatorial optimization problem with sparse rewards, since whether the structure matches can only be evaluated on a complete sequence.
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The goal of RNA inverse design is, given a target secondary structure, to find a nucleotide sequence whose minimum free energy (MFE) structure equals the target structure.
50%UnverifiedRNA inverse design is a combinatorial optimization problem with sparse rewards, since whether the structure matches can only be evaluated on a complete sequence.
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