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PersonWilliam Knowles

William Knowles

American chemist and one of the recipients of the 2001 Nobel Prize in Chemistry. He developed the BINAP ligand-rhodium catalyst system for asymmetric catalytic hydrogenation, which was applied to the industrial production of L-DOPA.

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Oct 12

The 2001 Nobel Prize in Chemistry was awarded to William Knowles, Ryoji Noyori, and Barry Sharpless in recognition of their pioneering contributions to chiral catalytic hydrogenation and chiral catalytic oxidation reactions.

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Oct 12

The BINAP ligand-rhodium catalyst system developed by William Knowles can efficiently catalyze the hydrogenation of prochiral olefins, generating a single chiral product with extremely high enantioselectivity, and was applied to the industrial production of the Parkinson's disease drug L-DOPA.

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