Unverified50% confidenceFactExact time
The loop extrusion model holds that the cohesin ring extrudes along DNA at a rate of about 0.5-1 kb per second until it stalls upon encountering a CTCF binding site in the correct orientation.
1
Sources
50%
Confidence
Long-term
Relevance
10/19/2026
First Seen
Sources
Related Entities
Related Claims
UnverifiedDistal enhancers contact target promoters through chromatin loops, and the motor protein cohesin extrudes DNA to form dynamic loops, building transcription hubs.73% similarUnverifiedEven if an enhancer and a promoter are separated by hundreds of thousands of bases in linear sequence, they may be physically proximate due to three-dimensional folding, thereby driving gene transcription.62% similarUnverifiedThe write latency of Chain Replication grows linearly with chain length; the longer the chain, the higher the end-to-end latency.59% similarUnverifiedThe Loop node processes records one by one through serialization, which can mitigate the risk of triggering API rate limits due to concurrent sending.57% similar
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