Two programs generated by SwarmRSI have actually been adopted by biologists in intestinal and spleen immunology research, where in the intestinal study the Spearman correlation coefficients of the post-processing representation MHC-II scores reached 0.77 and 0.69, higher than the 0.65 and 0.40 of RNA PCA; in the spleen study the metric improved from 0.045 to 0.102.