Unverified85% confidenceTradeoffTime unknown
NSAIDs镇痛效果强、起效快但胃肠道溃疡和肝肾风险高；加巴喷丁副作用小（主要为嗜睡）但对炎性痛效果弱，更适合神经性疼痛和辅助镇痛
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85%
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Long-term
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Unverified止痛越强越快的NSAIDs对胃肠道和肾脏负担越大；偶发轻中度痛经可选对乙酰氨基酚（对胃友好），频繁重度痛经再上布洛芬/萘普生88% similarUnverified镇痛效果与副作用风险成正比：NSAIDs镇痛强但伤肝肾胃，阿片类镇痛更强但有呼吸抑制和管制限制，慢性轻度疼痛应从低风险的NSAIDs或加巴喷丁起步而非直接上强效药85% similarUnverified止痛强度与副作用风险呈正相关：阿片类镇痛强但有镇静、便秘、呼吸抑制风险；NSAIDs较温和但伤胃肾。慢性温和管理选NSAIDs，急性剧痛短期用阿片类过渡84% similarUnverified对乙酰氨基酚止痛强度弱于布洛芬等NSAIDs类药物，中重度痛经可能镇痛效果不足83% similarUnverified吲哚美辛属于非甾体抗炎药（NSAID），消炎镇痛作用较强但胃肠道副作用也偏大；外用贴膏可大幅降低全身副作用，但长期大面积贴敷仍需注意83% similar
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