Unverified60% confidenceFactExact time
Kagan proposed that two or more chiral ligands can simultaneously bind to a metal to form a catalyst, and when the activity of the heterochiral complex is far lower than that of other types, the ratio of product enantiomers will exceed the ratio of the catalyst itself—a phenomenon known as the positive nonlinear effect.
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60%
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Long-term
Relevance
10/8/2026
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Related Claims
UnverifiedSoai developed asymmetric autocatalytic reactions, in which the reaction product itself acts as its own catalyst, capable of amplifying a tiny chiral bias starting from achiral raw materials.73% similarUnverifiedThe positive nonlinear effect means that high-purity products can be obtained without preparing the catalyst to extremely high purity, thereby significantly reducing production costs.65% similarUnverifiedThe Soai reaction uses pyrimidinyl aldehyde as the substrate to react with a dialkylzinc reagent to produce a chiral alcohol, which itself is the catalyst for the reaction, and its amplification mechanism is related to the fact that homochiral dimers are far more active than heterochiral dimers.62% similar
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