ADMET
A core evaluation framework in drug discovery encompassing five properties: Absorption, Distribution, Metabolism, Excretion, and Toxicity. These attributes are used to assess the druggability of candidate compounds, and AI models can predict these properties directly from molecular structures.
Timeline (last 90 days)
Candidate molecules generated by SpecOpt are accepted only if they simultaneously satisfy three criteria: molecular similarity, ADMET properties, and target-versus-off-target docking selectivity.
ADMET refers to the five evaluation dimensions in drug discovery: absorption, distribution, metabolism, excretion, and toxicity.
AI models can directly predict ADMET properties based on molecular structure, thereby screening out candidates with poor druggability at an early stage.
All Facts (3)
Candidate molecules generated by SpecOpt are accepted only if they simultaneously satisfy three criteria: molecular similarity, ADMET properties, and target-versus-off-target docking selectivity.
50%UnverifiedADMET refers to the five evaluation dimensions in drug discovery: absorption, distribution, metabolism, excretion, and toxicity.
50%UnverifiedAI models can directly predict ADMET properties based on molecular structure, thereby screening out candidates with poor druggability at an early stage.
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