Unverified50% confidenceEventExact time
In 1995, Soai and his colleagues reported a landmark asymmetric autocatalytic reaction: the addition of dialkylzinc reagents to pyrimidine-containing aldehydes, producing a chiral alcohol that can promote the reaction.
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10/12/2026
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UnverifiedThe Soai reaction was first reported in 1995, using an addition reaction between pyridinecarboxaldehyde and an organozinc reagent, in which the alcohol product can catalyze the next round of same-chirality product formation with extremely high efficiency.78% similarUnverifiedThe Soai reaction uses pyrimidinyl aldehyde as the substrate to react with a dialkylzinc reagent to produce a chiral alcohol, which itself is the catalyst for the reaction, and its amplification mechanism is related to the fact that homochiral dimers are far more active than heterochiral dimers.76% similarUnverifiedKenso Soai discovered and elucidated the "Soai reaction," an asymmetric autocatalytic reaction catalyzed by small organic molecules.70% similarUnverifiedThe Soai reaction is an addition reaction between pyridine-5-carbaldehyde and diisopropylzinc, with an amplification factor as high as 630,000-fold; the product is a chiral secondary alcohol that can catalyze the next round of reaction, forming an autocatalytic cycle.62% similarUnverifiedThe SOAI reaction is an artificial chemical reaction that is not entirely the same as biochemical processes within living organisms, but it provides clues for exploring the origin of single-handedness in life on Earth.55% similar
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